Eland is a computer program that aligns short oligonucleotides against a reference genome. It is written by Anthony Cox from the Illumina company. The source codes are freely available to machine buyers. Eland is the first program for short read alignment and it profoundly influences most of its successors.
Algorithm
Eland guarantees full sensitivity for hits with [...]
Posts Tagged ‘NGS’
The Eland Short Read Aligner
Posted in research, tagged algorithm, alignment, NGS on August 24, 2008 | Leave a Comment »
Biased Benchmarks on Short Read Aligners: ZOOM
Posted in research, tagged alignment, benchmark, NGS, opinion on August 19, 2008 | Leave a Comment »
ZOOM [PMID:18684737] is still unavailable even when the manuscript goes online. For the time being, there is no way to confirm whether their benchmarks are unbiased. Fortunately, we can collect some information from what they have presented. In the ZOOM paper, the authors give the memory consumption of ZOOM. It is 2.9GB for 12 million [...]